AMG 487 S-enantiomer

Names

[ CAS No. ]:
473720-30-8

[ Name ]:
AMG 487 S-enantiomer

[Synonym ]:
Benzeneacetamide, N-[(1S)-1-[3-(4-ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)-
N-{(1S)-1-[3-(4-Ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl]ethyl}-N-(3-pyridinylmethyl)-2-[4-(trifluoromethoxy)phenyl]acetamide
AMG 487 (S-enantiomer)

Biological Activity

[Description]:

AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an antagonist of the chemokine receptor CXCR3.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Others

[In Vitro]

AMG 487 S-enantiomer (Compound 3.74) is the S enantiomer of AMG 487[1].

[References]

[1]. CXCR3 ANTAGONISTS. WIPO Patent Application WO/2002/083143


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
750.0±70.0 °C at 760 mmHg

[ Molecular Formula ]:
C32H28F3N5O4

[ Molecular Weight ]:
603.591

[ Flash Point ]:
407.4±35.7 °C

[ Exact Mass ]:
603.209351

[ LogP ]:
3.76

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.606

[ Storage condition ]:
2-8℃

Related Compounds