Fmoc-NH-PEG4-CH2COOH

Names

[ Name ]:
Fmoc-NH-PEG4-CH2COOH

[Synonym ]:
14-methylpentadecyl bromide
14-morpholin-4-yl-daunomycin
14-Morpholino-daunomycin
14-methyl-1-bromopentadecane
Pentadecane,1-bromo-14-methyl

Biological Activity

[Description]:

Fmoc-NH-PEG4-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Maggie Lu, et al. Linker-wirkstoff und antikörper-wirkstoff-konjugat (adc) damit. EP3335734A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₃₁NO₈

[ Molecular Weight ]:
473.51600

[ Exact Mass ]:
473.20500

[ PSA ]:
116.04000

[ LogP ]:
2.88050

[ Storage condition ]:
2-8°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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