8-azidoadenosine

Names

[ Name ]:
8-azidoadenosine

[Synonym ]:
8-azidoadenosine

Biological Activity

[Description]:

8-Azidoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Chemical & Physical Properties

[ Melting Point ]:
>200ºC (dec.)

[ Molecular Formula ]:
C₁₀H₁₂N₈O₄

[ Molecular Weight ]:
308.25

[ Exact Mass ]:
308.09800

[ PSA ]:
189.29000

[ Storage condition ]:
Amber Vial, Refrigerator, Under Inert Atmosphere

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.