4-Bromobenzylamine

Names

[ Name ]:
4-Bromobenzylamine

[Synonym ]:
p-Bromobenzylamine
4-Bromobenzylamine
1-(4-Bromophenyl)methanamine
Benzenemethanamine, 4-bromo-
EINECS 223-559-4
MFCD00047931
(4-bromophenyl)methanamine

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
248.9±15.0 °C at 760 mmHg

[ Melting Point ]:
25 °C(lit.)

[ Molecular Formula ]:
C₇H₈BrN

[ Molecular Weight ]:
186.049

[ Flash Point ]:
104.3±20.4 °C

[ Exact Mass ]:
184.984009

[ PSA ]:
26.02000

[ LogP ]:
1.86

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.590

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R21/22;R34

[ Safety Phrases ]:
S26-S28-S36/37/39-S45

[ RIDADR ]:
UN 3259 8/PG 2

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism.

Proc. Natl. Acad. Sci. U. S. A. 111(23) , 8428-33, (2014)

Voltage-gated sodium channels are important targets for the development of pharmaceutical drugs, because mutations in different human sodium channel isoforms have causal relationships with a range of ...

Common metal of copper(0) as an efficient catalyst for preparation of nitriles and imines by controlling additives.

Chem. Commun. (Camb.) 50(42) , 5637-40, (2014)

A novel, efficient, convenient and environmentally friendly approach for the synthesis of nitriles and imines from primary amines has been developed. Using commercially available red copper as the cat...

Novel series of substituted biphenylmethyl urea derivatives as MCH-R1 antagonists for the treatment of obesity.

Bioorg. Med. Chem. 15(11) , 3896-911, (2007)

We have designed and synthesized two novel series of MCH-R1 antagonists based on a substituted biphenylmethyl urea core. SAR was explored, suggesting that optimal binding with the receptor was achieve...