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Amadacycline

Names

[ CAS No. ]:
389139-89-3

[ Name ]:
Amadacycline

[Synonym ]:
Omadacycline (USAN)
2-Naphthacenecarboxamide,4,7-bis(dimethylamino)-9-[[(2,2-dimethylpropyl)amino]methyl]-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-,(4S,4aS,5aR,12aS)
PTK-0796
Amadacycline
Omadacycline

Biological Activity

[Description]:

Omadacycline is a new tetracycline antibiotic in the pipeline, which can inhibit the 30s subunit of bacterial ribosome.IC50 Value:Target: Antibacterialin vitro: in vivo: Clinical trial: Phase III Study to Compare the Safety and Efficacy of PTK-0796 in Patients With Complicated Skin and Skin Structure Infection (CSSSI).

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Bacterial
Research Areas >> Infection

[References]

[1]. Schmitz J, Holzgrabe U. Amadacyclin - a new tetracycline antibiotic in the pipeline. Pharm Unserer Zeit. 2010 Mar;39(2):94-5.


[Related Small Molecules]

Puromycin 2HCl | Geneticin | Tunicamycin | Hygromycin B | Salinomycin | Avibactam sodium | Neomycin sulfate | Vaborbactam | Methicillin SodiuM | Rifampicin | Metronidazole | Carbenicillin disodium | Ceftazidime | Eravacycline dihydrochloride | cefotaxime sodium

Chemical & Physical Properties

[ Molecular Formula ]:
C29H40N4O7

[ Molecular Weight ]:
556.65000

[ Exact Mass ]:
556.29000

[ PSA ]:
177.65000

[ LogP ]:
2.70630

[ Storage condition ]:
2-8℃

Related Compounds

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