MAO-B-IN-26

Names

[ Name ]:
MAO-B-IN-26

Biological Activity

[Description]:

MAO-B-IN-26 (Compound IC9) is a MAO-B and acetylcholinesterase inhibitor. MAO-B-IN-26 protects SH?SY5Y cells against Aβ induced cytotoxicity, morphological changes, ROS generation and membrane damage. MAO-B-IN-26 also inhibits Aβ induced autophagy and apoptosis. MAO-B-IN-26 can be used as a neuroprotective agent against Alzheimer’s disease[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase

Signaling Pathways >> Autophagy >> Autophagy

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> AChE

[References]

[1]. Sasidharan R, et al. MAO-B Inhibitor (2E)-3-(4-Bromophenyl)-1-(1H-indol-3-yl) prop-2-en-1-one as a Neuroprotective Agent Against Alzheimer's Disease. Neurochem Res. 2023 Oct 9.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₂BrNO

[ Molecular Weight ]:
326.19

Related Compounds

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