ACDPP Hydrochloride

Names

[ Name ]:
ACDPP Hydrochloride

Biological Activity

[Description]:

ACDPP is a specific mGluR5 antagonist. ACDPP partially bolcks the increase of fragile X mental retardation protein (FMRP) caused by DHPG (HY-12598A) (group I mGluR Agonist)[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> mGluR

Research Areas >> Neurological Disease

[Target]

mGluR5[1]

[References]

[1]. Wang H, et al. Roles of calcium-stimulated adenylyl cyclase and calmodulin-dependent protein kinase IV in the regulation of FMRP by group I metabotropic glutamate receptors. J Neurosci. 2008 Apr 23;28(17):4385-97.

Chemical & Physical Properties

[ Boiling Point ]:
473.6ºC at 760 mmHg

[ Molecular Formula ]:
C₁₂H₁₃ClN₆O

[ Molecular Weight ]:
292.72

[ Flash Point ]:
240.3ºC

[ Exact Mass ]:
328.06100

[ PSA ]:
97.03000

[ LogP ]:
2.88170

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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