37804-11-8

37804-11-8 structure

Name: ACDPP Hydrochloride
Chemical Name: 3-amino-6-chloro-5-(dimethylamino)-N-pyridin-3-ylpyrazine-2-carboxamide,hydrochloride
CAS Number: 37804-11-8
Molecular Formula: C₁₂H₁₃ClN₆O
Molecular Weight: 292.72
Catalog: Signaling Pathways GPCR/G Protein mGluR
Create Date: 2017-07-07 19:48:25
Modify Date: 2024-01-24 07:25:15
ACDPP is a specific mGluR5 antagonist. ACDPP partially bolcks the increase of fragile X mental retardation protein (FMRP) caused by DHPG (HY-12598A) (group I mGluR Agonist)[1].

Name	3-amino-6-chloro-5-(dimethylamino)-N-pyridin-3-ylpyrazine-2-carboxamide,hydrochloride

Description	ACDPP is a specific mGluR5 antagonist. ACDPP partially bolcks the increase of fragile X mental retardation protein (FMRP) caused by DHPG (HY-12598A) (group I mGluR Agonist)[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
Target	mGluR5[1]
References	[1]. Wang H, et al. Roles of calcium-stimulated adenylyl cyclase and calmodulin-dependent protein kinase IV in the regulation of FMRP by group I metabotropic glutamate receptors. J Neurosci. 2008 Apr 23;28(17):4385-97.

504-29-0

27245-43-8

37804-11-8

Precursor 2
504-29-0 27245-43-8
DownStream 0