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4BP-TQS

Names

[ CAS No. ]:
360791-49-7

[ Name ]:
4BP-TQS

[Synonym ]:
3H-Cyclopenta[c]quinoline-8-sulfonamide, 4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-
4-(4-Bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide
MFCD00981752
4BP-TQS

Biological Activity

[Description]:

4BP-TQS is a potent allosteric agonist of α7 nAChR. 4BP-TQS activates nAChRs via an allosteric transmembrane site[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR
Signaling Pathways >> Neuronal Signaling >> nAChR
Research Areas >> Neurological Disease

[References]

[1]. Gill JK, et al. Agonist activation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site. Proc Natl Acad Sci U S A. 2011;108(14):5867-5872.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
566.2±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H17BrN2O2S

[ Molecular Weight ]:
405.309

[ Flash Point ]:
296.2±32.9 °C

[ Exact Mass ]:
404.019409

[ LogP ]:
2.98

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.655

[ Storage condition ]:
20°C

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Related Compounds