TN-16

[Description]:

[Related Catalog]:

[References]

[ Density]:
1.249g/cm3

[ Boiling Point ]:
532.7ºC at 760 mmHg

[ Melting Point ]:
182-185 °C

[ Molecular Formula ]:
C₁₉H₁₈N₂O₂

[ Molecular Weight ]:
306.35800

[ Flash Point ]:
195.5ºC

[ Exact Mass ]:
306.13700

[ PSA ]:
58.20000

[ LogP ]:
3.08450

[ Index of Refraction ]:
1.648

[ Storage condition ]:
2-8℃

Click to get detail MSDS

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H317-H400

[ Precautionary Statements ]:
P273-P280

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
43-50/53

[ Safety Phrases ]:
36/37-60-61

[ RIDADR ]:
UN 3077 9 / PGIII

CENP-C and CENP-I are key connecting factors for kinetochore and CENP-A assembly.

J. Cell Sci. 128 , 4572-87, (2015)

Although it is generally accepted that chromatin containing the histone H3 variant CENP-A is an epigenetic mark maintaining centromere identity, the pathways leading to the formation and maintenance o...

Inhibition of microtubule assembly in vitro by TN-16, a synthetic antitumor drug.

FEBS Lett. 155(2) , 273-6, (1983)

An antitumor drug, 3-(1-anilinoethylidene)-5-benzylpyrrolidine-2,4-dione (TN-16) inhibited the assembly of porcine brain microtubules in vitro. The assembly induced by taxol was also suppressed by the...

Localization of Fas ligand in cytoplasmic granules of CD8+ cytotoxic T lymphocytes and natural killer cells: participation of Fas ligand in granule exocytosis model of cytotoxicity.

Biochem. Biophys. Res. Commun. 296(2) , 328-36, (2002)

Fas ligand (FasL) has been implicated in cytotoxic T lymphocyte (CTL)- and natural killer (NK) cell-mediated cytotoxicity. In the present study, we investigated the localization of FasL in murine CTL ...

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