Methanesulfonamide
Names
[ CAS No. ]:
3144-09-0
[ Name ]:
Methanesulfonamide
[Synonym ]:
MFCD00007940
aminosulfane dioxide
Methanesulfonamide
Methylsulfonamide
methansulfonamid
methanesulfonyl amine
Methane sulfonamide
EINECS 221-553-6
methylsulfonylamine
Methanesulphonamide
Biological Activity
[Description]:
[Related Catalog]:
[In Vitro]
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
208.2±23.0 °C at 760 mmHg
[ Melting Point ]:
85-89 °C(lit.)
[ Molecular Formula ]:
CH5NO2S
[ Molecular Weight ]:
95.12
[ Flash Point ]:
79.7±22.6 °C
[ Exact Mass ]:
95.004097
[ PSA ]:
68.54000
[ LogP ]:
-1.29
[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.460
[ Storage condition ]:
2~8℃
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
29350090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2935009090
[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%
Articles
Arthritis. Res. Ther. 17 , 321, (2015)
The endocannabinoid system modulates function of immune cells and mesenchymal cells such as fibroblasts, which contribute to cartilage destruction in rheumatoid arthritis (RA). The aim of the study wa...
Inhibition of cyclooxygenase-2 causes a decrease in coronary flow in diabetic mice. The possible role of PGE2 and dysfunctional vasodilation mediated by prostacyclin receptor.J. Physiol. Biochem. 71 , 351-8, (2015)
Several lines of evidence suggest that cyclooxygenase-2 (COX-2) activity can have a beneficial role in the maintenance of vascular tone of the blood vessels in diabetes. Specifically, the increased pr...
In vitro antitumor mechanism of (E)-N-(2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridin-3-yl)methanesulfonamide.Mol. Pharmacol. 87(1) , 18-30, (2015)
ON01910.Na [sodium (E)-2-(2-methoxy-5-((2,4,6-trimethoxystyrylsulfonyl)methyl)phenylamino)acetate; Rigosertib, Estybon], a styryl benzylsulfone, is a phase III stage anticancer agent. This non-ATP com...