ATR-IN-22

Names

[ CAS No. ]:
2905312-07-2

[ Name ]:
ATR-IN-22

Biological Activity

[Description]:

ATR-IN-22 (Compound 34) is an orally active ATR inhibitor. ATR-IN-22 inhibits MIAPaCa-2 proliferation (IC50 <1 μM). ATR-IN-22 shows anti-tumor activity in colon cancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> ATM/ATR
Signaling Pathways >> PI3K/Akt/mTOR >> ATM/ATR

[References]

[1]. Xie, Yuli, et al. Naphthyridine derivative as ATR inhibitor and method for preparing same. Patent. WO2023016529. 2023-02-16.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H31N7O

[ Molecular Weight ]:
445.56

Related Compounds