JNK3 inhibitor-1

Names

[ Name ]:
JNK3 inhibitor-1

Biological Activity

[Description]:

JNK3 inhibitor-1 is a potent and selective JNK3 inhibitor (IC50 = 0.005 μM). JNK3 inhibitor-1 is orally bioavailable and brain penetrant.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> MAPK/ERK Pathway >> JNK

[References]

[1]. Feng Y, et al. N-Aromatic-Substituted Indazole Derivatives as Brain-Penetrant and Orally Bioavailable JNK3 Inhibitors. ACS Med Chem Lett. 2021 Sep 21;12(10):1546-1552.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₁₇ClFN₅O₂S

[ Molecular Weight ]:
457.91

Related Compounds

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