p38-α MAPK-IN-4

Names

[ CAS No. ]:
2396754-57-5

[ Name ]:
p38-α MAPK-IN-4

Biological Activity

[Description]:

p38-α MAPK-IN-4 (Compound 69) is a selective p38α MAPK inhibitor with an IC50 of 1.5 µM. p38-α MAPK-IN-4 rapidly and strongly prevents the development of mechanical allodynia (MA) in vivo[1].

[Related Catalog]:

Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK
Research Areas >> Inflammation/Immunology
Research Areas >> Neurological Disease

[Target]

p38α MAPK:1.5 μM (IC50)


[References]

[1]. Visseq A, et al. Pyridin-2(1H)one derivatives: A possible new class of therapeutics for mechanical allodynia. Eur J Med Chem. 2020 Feb 1;187:111917.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H13BrN2O

[ Molecular Weight ]:
341.20

Related Compounds