p38-α MAPK-IN-1

p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay.

Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK

Research Areas >> Others

IC50: 2300 nM (p38-α, in EFC assay), 5500 nM (p38-α, in HTRF assay)[1]

p38-α MAPK-IN-1 (Compound 12) is an inhibitor of MAPK14 (p38-α)>, with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay[1].

[1]. Kluter S, et al. Displacement assay for the detection of stabilizers of inactive kinase conformations. J Med Chem. 2010 Jan 14;53(1):357-67.

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