UCSF678

Names

[ Name ]:
UCSF678

Biological Activity

[Description]:

UCSF678 is a 42 nM arrestin-biased partial agonist at the 5-HT5AR with a more restricted off-target profile and decreased assay liabilities. UCSF678 is a selective probe with which to study the function of the 5-HT5AR[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[References]

[1]. Levit Kaplan A, et al. Structure-Based Design of a Chemical Probe Set for the 5-HT5A Serotonin Receptor. J Med Chem. 2022;65(5):4201-4217.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₈N₂O₂S

[ Molecular Weight ]:
290.38

Related Compounds

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