2361697-55-2

2361697-55-2 structure

Name: UCSF678
Chemical Name: UCSF678
CAS Number: 2361697-55-2
Molecular Formula: C₁₅H₁₈N₂O₂S
Molecular Weight: 290.38
Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
Create Date: 2022-04-09 06:14:17
Modify Date: 2025-08-20 17:01:45
UCSF678 is a 42 nM arrestin-biased partial agonist at the 5-HT5AR with a more restricted off-target profile and decreased assay liabilities. UCSF678 is a selective probe with which to study the function of the 5-HT5AR[1].

Name	UCSF678

Description	UCSF678 is a 42 nM arrestin-biased partial agonist at the 5-HT5AR with a more restricted off-target profile and decreased assay liabilities. UCSF678 is a selective probe with which to study the function of the 5-HT5AR[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
References	[1]. Levit Kaplan A, et al. Structure-Based Design of a Chemical Probe Set for the 5-HT5A Serotonin Receptor. J Med Chem. 2022;65(5):4201-4217.

Molecular Formula	C₁₅H₁₈N₂O₂S
Molecular Weight	290.38