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NS1219

Names

[ CAS No. ]:
233603-81-1

[ Name ]:
NS1219

Biological Activity

[Description]:

NS1219 ((R)-SPD502) is the isomer of NS 1209 HY-15074. NS1209 is a selective AMPA receptor antagonist with neuroprotective activity. NS1209 can be used for the research of stroke, neuropathic pain and epilepsy[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> iGluR
Research Areas >> Neurological Disease
Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR

[References]

[1]. Jan M Keppel Hesselink, et al. NS1209/SPD 502, A Novel Selective AMPA Antagonist for Stroke, Neuropathic Pain or Epilepsy? Drug Development Lessons Learned. Drug Dev Res. 2017 Mar;78(2):75-80.  

Chemical & Physical Properties

[ Molecular Formula ]:
C24H28N4O7S

[ Molecular Weight ]:
516.56700

[ Exact Mass ]:
516.16800

[ PSA ]:
157.22000

[ LogP ]:
2.25690

Related Compounds