233603-81-1

233603-81-1 structure

Name: NS1219
Chemical Name: (R)-2-[5-(4-dimethylsulfamoyl-phenyl)-8-methyl-2-oxo-1,2,6,7,8,9- hexahydro-pyrrolo [3,2-h]isoquinolin-3-ylideneaminooxy]-4-hydroxy-butyric acid
CAS Number: 233603-81-1
Molecular Formula: C₂₄H₂₈N₄O₇S
Molecular Weight: 516.56700
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2018-06-29 20:41:53
Modify Date: 2024-04-07 14:07:32
NS1219 ((R)-SPD502) is the isomer of NS 1209 HY-15074. NS1209 is a selective AMPA receptor antagonist with neuroprotective activity. NS1209 can be used for the research of stroke, neuropathic pain and epilepsy[1].

Name	(R)-2-[5-(4-dimethylsulfamoyl-phenyl)-8-methyl-2-oxo-1,2,6,7,8,9- hexahydro-pyrrolo [3,2-h]isoquinolin-3-ylideneaminooxy]-4-hydroxy-butyric acid

Description	NS1219 ((R)-SPD502) is the isomer of NS 1209 HY-15074. NS1209 is a selective AMPA receptor antagonist with neuroprotective activity. NS1209 can be used for the research of stroke, neuropathic pain and epilepsy[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
References	[1]. Jan M Keppel Hesselink, et al. NS1209/SPD 502, A Novel Selective AMPA Antagonist for Stroke, Neuropathic Pain or Epilepsy? Drug Development Lessons Learned. Drug Dev Res. 2017 Mar;78(2):75-80.