Pirimicarb

Names

[ Name ]:
Pirimicarb

[Synonym ]:
Pirimor G
2-(Dimethylamino)-5,6-dimethylpyrimidin-4-yl-dimethylcarbamat
4,5-dimethyl-2-dimethylamino-6-dimethylcarbamoyloxy-pyrimidine
Fernos
2-(Dimethylamino)-5,6-dimethylpyrimidin-4-yl dimethylcarbamate
Primicarbe
2-dimethylamino-4-dimethylcarbamoyloxy-5,6-dimethyl-pyrimidine
2-dimethylamino-5,6-dimethylpyrimidin-4-yl N,N-dimethylcarbamate
Aphox
2-(Dimethylamino)-5,6-dimethyl-4-pyrimidinyl dimethylcarbamate
Rapid
2-(dimethylamino)-5,6-dimethyl-4-pyrimidinyl N,N-dimethylcarbamate
MFCD00055520
5,6-dimethyl-2-dimethylamino-4-pyrimidinyl dimethylcarbamate
Pyrimor
Pirimicarb
pyrimicarbe
Pirimor
Carbamic acid, N,N-dimethyl-, 2-(dimethylamino)-5,6-dimethyl-4-pyrimidinyl ester
[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate
EINECS 245-430-1
Aficida
2-dimethylamino-5,6-dimethylpyrimidin-4-yl dimethylcarbamate

Biological Activity

[Description]:

Pirimicarb is a fast-acting selective carbamate insecticide on a wide range of crops including cereals, sugar beet, potatoes, fruits and vegetables. Pirimicarb is an AChE inhibitor and an acaricide[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> AChE

[References]

[1]. Clémence Riva, et al. Effect of Oral Exposure to the Acaricide Pirimicarb, a New Varroacide Candidate, on Apis Mellifera Feeding Rate. Pest Manag Sci. 2018 Aug;74(8):1790-1797.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
373.4±52.0 °C at 760 mmHg

[ Melting Point ]:
90.5°C

[ Molecular Formula ]:
C₁₁H₁₈N₄O₂

[ Molecular Weight ]:
238.286

[ Flash Point ]:
179.6±30.7 °C

[ Exact Mass ]:
238.142975

[ PSA ]:
58.56000

[ LogP ]:
1.70

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.549

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EZ9100000

CHEMICAL NAME :: Carbamic acid, dimethyl-, 2-(dimethylamino)-5,6-dimethyl-4-pyrimidinyl ester

CAS REGISTRY NUMBER :: 23103-98-2

BEILSTEIN REFERENCE NO. :: 0663442

LAST UPDATED :: 199612

DATA ITEMS CITED :: 15

MOLECULAR FORMULA :: C11-H18-N4-O2

MOLECULAR WEIGHT :: 238.33

WISWESSER LINE NOTATION :: T6N CNJ BN1&1 D1 E1 FOVN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 68 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - pigeon

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: 54 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: 17200 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - wild bird species

DOSE/DURATION :: 30 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: Mutation test systems - not otherwise specified

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 2 mg/kg

REFERENCE :: CYGEDX Cytology and Genetics (English Translation). Translation of TGANAK. (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 1974- Volume(issue)/page/year: 14(6),38,1980 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 0.05 mg/m3 JAN 1993

Safety Information

[ Symbol ]:

GHS06, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H410

[ Precautionary Statements ]:
P273-P501

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic;N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R25;R50/53

[ Safety Phrases ]:
S22-S37-S45-S60-S61-S36-S26-S16

[ RIDADR ]:
UN 2811

[ RTECS ]:
EZ9100000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2933599015

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933599015

[ Summary ]:
2933599015 2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl dimethylcarbamate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

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