Anticancer agent 60

Names

[ CAS No. ]:
2162169-14-2

[ Name ]:
Anticancer agent 60

Biological Activity

[Description]:

Anticancer agent 60 (compound 3h) has antiproliferative activity against human HepG2 cells (IC50 = 4.13 μM) and presents antitumor efficacy in a human HepG2 xenograft mouse model[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin
Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin

[Target]

IC50: 4.13 ± 0.54 μM in HepG2, 6.06 ± 0.46 μM in Bel-7402, 15.04 ± 0.74 μM in MCF-7[1]


[References]

[1]. Liu Y, et al. Synthesis and structure-activity relationship study of water-soluble carbazole sulfonamide derivatives as new anticancer agents. Eur J Med Chem. 2020;191:112181.

Chemical & Physical Properties

[ Molecular Formula ]:
C27H33N5O4S

[ Molecular Weight ]:
523.65

Related Compounds

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