2162169-14-2

2162169-14-2 structure

Name: Anticancer agent 60
Chemical Name: Anticancer agent 60
CAS Number: 2162169-14-2
Molecular Formula: C₂₇H₃₃N₅O₄S
Molecular Weight: 523.65
Catalog: Signaling Pathways Cell Cycle/DNA Damage Microtubule/Tubulin
Create Date: 2022-08-12 00:07:44
Modify Date: 2024-02-22 12:07:11
Anticancer agent 60 (compound 3h) has antiproliferative activity against human HepG2 cells (IC50 = 4.13 μM) and presents antitumor efficacy in a human HepG2 xenograft mouse model[1].

Name	Anticancer agent 60

Description	Anticancer agent 60 (compound 3h) has antiproliferative activity against human HepG2 cells (IC50 = 4.13 μM) and presents antitumor efficacy in a human HepG2 xenograft mouse model[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
Target	IC50: 4.13 ± 0.54 μM in HepG2, 6.06 ± 0.46 μM in Bel-7402, 15.04 ± 0.74 μM in MCF-7[1]
References	[1]. Liu Y, et al. Synthesis and structure-activity relationship study of water-soluble carbazole sulfonamide derivatives as new anticancer agents. Eur J Med Chem. 2020;191:112181.

Molecular Formula	C₂₇H₃₃N₅O₄S
Molecular Weight	523.65