Neurokinin antagonist 1

Neurokinin antagonist 1 is a Neurokinin antagonist extracted from patent WO1998045262A1.

Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor

Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor

Research Areas >> Inflammation/Immunology

Neurokinin[1]

The invention in the patent WO1998045262A1 refers to antagonists of the interaction between the P substance and the NK-1 receptor, the process for their preparation, and their use in pharmaceutical compositions which may be used in the treatment of pathological forms in which the P substance receptor is involved, and in particular in the treatment of the inflammation of airways, such as asthma and rhinitis, and in the treatment of emesis[1].

[1]. Sisto Alessandro, et al. Pseudo-peptide compounds as antagonists of neurokinines. WO1998045262A1.

Substance P acetate salt | rolapitant | SB-222200 | Fezolinetant | Netupitant | [Sar9,Met(O2)11]-Substance P TFA | MLE-4901 | Succinyl-(Asp6,N-Me-Phe8)-Substance P (6-11) | Maropitant | NKP608 | Serlopitant | Talnetant | Y1 receptor antagonist 1 | [bAla8]-Neurokinin A(4-10)