Sortilin antagonist 1

Names

[ CAS No. ]:
2691846-93-0

[ Name ]:
Sortilin antagonist 1

Biological Activity

[Description]:

Sortilin antagonist 1 (compound 44) is a sortilin antagonist with an IC50 value of 20 nM for inhibiting Neurotensin (NTS) binds to sortilin. Neurotensin is a sortilin ligand. Sortilin antagonist 1 can be used for the research of neurological disease[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Neurotensin Receptor
Research Areas >> Neurological Disease

[References]

[1]. Kjoelby, Mads Fuglsang, et al. A sortilin antagonist for use in the prevention or treatment of hearing loss. WO2022074119. 2022.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H24N2O4

[ Molecular Weight ]:
356.42

Related Compounds