FRα-IN-1

Names

[ CAS No. ]:
2028296-64-0

[ Name ]:
FRα-IN-1

Biological Activity

[Description]:

FRα-IN-1 (Compound 4) is a tumor-targeting agent. FRα-IN-1 shows selective anticancer activity towards folate receptors (FRα and FRβ) expression cells[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Antifolate

[Target]

Folate receptor[1]

[References]

[1]. Golani LK, et al. Design, synthesis and biological evaluation of novel pyrrolo[2,3-d]pyrimidine as tumor-targeting agents with selectivity for tumor uptake by high affinity folate receptors over the reduced folate carrier. Bioorg Med Chem. 2020 Jun 15;28(12):115544.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₄N₆O₆

[ Molecular Weight ]:
456.45

Related Compounds

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