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2028296-64-0

2028296-64-0 structure

2028296-64-0 structure

Name: FRα-IN-1
Chemical Name: FRα-IN-1
CAS Number: 2028296-64-0
Molecular Formula: C₂₁H₂₄N₆O₆
Molecular Weight: 456.45
Catalog: Signaling Pathways Cell Cycle/DNA Damage Antifolate
Create Date: 2022-07-01 10:31:35
Modify Date: 2024-01-14 02:55:57
FRα-IN-1 (Compound 4) is a tumor-targeting agent. FRα-IN-1 shows selective anticancer activity towards folate receptors (FRα and FRβ) expression cells[1].

Name	FRα-IN-1

Description	FRα-IN-1 (Compound 4) is a tumor-targeting agent. FRα-IN-1 shows selective anticancer activity towards folate receptors (FRα and FRβ) expression cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Antifolate
Target	Folate receptor[1]
References	[1]. Golani LK, et al. Design, synthesis and biological evaluation of novel pyrrolo[2,3-d]pyrimidine as tumor-targeting agents with selectivity for tumor uptake by high affinity folate receptors over the reduced folate carrier. Bioorg Med Chem. 2020 Jun 15;28(12):115544.

Molecular Formula	C₂₁H₂₄N₆O₆
Molecular Weight	456.45

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