VU 6001966

Names

[ CAS No. ]:
2009052-76-8

[ Name ]:
VU 6001966

Biological Activity

[Description]:

A potent and selective, CNS penetrant mGlu2 negative allosteric modulator with IC50 of 78 nM; shows no inhibition for mGlu3 (IC50>30 uM); represents an exciting lead series for potential mGlu2 PET tracer development.

[References]

References 1. Bollinger KA, et al. ACS Med Chem Lett. 2017 Aug 3;8(9):919-924. View Related Products by Target mGluR

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₅FN₄O₂

[ Molecular Weight ]:
326.331

Related Compounds

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