POL1-IN-1

Names

[ Name ]:
POL1-IN-1

Biological Activity

[Description]:

POL1-IN-1 is a RNA polymerase 1 (POL1, also known as Pol I) inhibitor with an IC50 of less than 0.5 uM. POL1-IN-1 inhibits ribosome biogenesis by inhibiting POL1 transcription[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

[References]

[1]. Mustapha Haddach. Compositions, uses and methods for making them. US9758518B2.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₀N₆

[ Molecular Weight ]:
356.42400

[ Exact Mass ]:
356.17500

[ PSA ]:
69.25000

[ LogP ]:
3.48778

[ Storage condition ]:
-20°C

Safety Information

[ Hazard Codes ]:
Xn

Related Compounds

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