TAK-071

Names

[ CAS No. ]:
1820812-16-5

[ Name ]:
TAK-071

Biological Activity

[Description]:

TAK-071 is a novel muscarinic acetylcholine receptor 1 (M1R) positive allosteric modulator. EC50 of TAK-071 M1R agonist activities is 520 nM[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> mAChR

Signaling Pathways >> GPCR/G Protein >> mAChR

Research Areas >> Neurological Disease

[Target]

EC50: 520 nM (M1R)[1]

[References]

[1]. Sako Y, et al. TAK-071, a novel M1 positive allosteric modulator with low cooperativity, improves cognitive function in rodents with few cholinergic side effects. Neuropsychopharmacology. 2018 Aug 1. doi: 10.1038/s41386-018-0168-8.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₄FN₃O₃

[ Molecular Weight ]:
421.46

[ Storage condition ]:
2-8℃

Related Compounds

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