1820812-16-5

1820812-16-5 structure

Name: TAK-071
Chemical Name: TAK-071
CAS Number: 1820812-16-5
Molecular Formula: C₂₄H₂₄FN₃O₃
Molecular Weight: 421.46
Catalog: Signaling Pathways GPCR/G Protein mAChR
Create Date: 2019-03-03 18:59:11
Modify Date: 2024-01-11 11:13:01
TAK-071 is a novel muscarinic acetylcholine receptor 1 (M1R) positive allosteric modulator. EC50 of TAK-071 M1R agonist activities is 520 nM[1].

Name	TAK-071

Description	TAK-071 is a novel muscarinic acetylcholine receptor 1 (M1R) positive allosteric modulator. EC50 of TAK-071 M1R agonist activities is 520 nM[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Neurological Disease
Target	EC50: 520 nM (M1R)[1]
References	[1]. Sako Y, et al. TAK-071, a novel M1 positive allosteric modulator with low cooperativity, improves cognitive function in rodents with few cholinergic side effects. Neuropsychopharmacology. 2018 Aug 1. doi: 10.1038/s41386-018-0168-8.