p-hydroxyphenylacetamide

Names

[ Name ]:
p-hydroxyphenylacetamide

[Synonym ]:
MFCD00017145
4-Hydroxybenzeneacetamide
2-(4-Hydroxyphenyl)-ethylamide
Benzeneethanimidic acid, 4-hydroxy-
p-hydroxyphenylacetamide
EINECS 241-235-0
Benzeneacetamide, 4-hydroxy-
2-(4-Hydroxyphenyl)ethanimidic acid
2-(4-Hydroxyphenyl)acetamide
Atenolol Impurity 1

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
339.4±44.0 °C at 760 mmHg

[ Melting Point ]:
176-178 °C(lit.)

[ Molecular Formula ]:
C₈H₉NO₂

[ Molecular Weight ]:
151.163

[ Flash Point ]:
159.1±28.4 °C

[ Exact Mass ]:
151.063324

[ PSA ]:
63.32000

[ LogP ]:
0.13

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.566

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AC3851500

CHEMICAL NAME :: Acetamide, 2-(p-hydroxyphenyl)-

CAS REGISTRY NUMBER :: 17194-82-0

BEILSTEIN REFERENCE NO. :: 2085984

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H9-N-O2

MOLECULAR WEIGHT :: 151.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg/24H (Continuous)

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 224,209,1989

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AC3851500

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Monitoring 2-phenylethanamine and 2-(3-hydroxyphenyl)acetamide sulfate in doping controls.

Drug Test. Anal. 7 , 1057-62, (2015)

2-Phenylethanamine (phenethylamine, PEA) represents the core structure of numerous drugs with stimulant-like properties and is explicitly featured as so-called specified substance on the World Anti-Do...

Diode array detection and simultaneous quantitation of the coeluting atenolol-related synthetic route impurities, PPA-Diol.

J. Chromatogr. Sci. 29(10) , 450-6, (1991)

The diode array multichannel detector is used to acquire spectral information at specified intervals in the elution profile of atenolol and its related impurities for post-chromatographic data analysi...