(R)-(+)-Atenolol

Names

[ Name ]:
(R)-(+)-Atenolol

[Synonym ]:
Prenormin
MFCD00074917
2-[4-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide

Biological Activity

[Description]:

(R)-(+)-Atenolol is the less active enantiomer of the (R,S)-atenolol. (R,S)-atenolol is a β-adrenergic receptor antagonist[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Batra S, et al. Bioassay, determination and separation of enantiomers of atenolol by direct and indirect approaches using liquid chromatography: A review. Biomed Chromatogr. 2018 Jan;32(1).

[2]. Stoschitzky K, et al. Stereoselective features of (R)- and (S)-atenolol: clinical pharmacological, pharmacokinetic, and radioligand binding studies. Chirality. 1993;5(1):15-9.

Chemical & Physical Properties

[ Density]:
1.125g/cm3

[ Boiling Point ]:
508ºC at 760mmHg

[ Melting Point ]:
148-152ºC(lit.)

[ Molecular Formula ]:
C₁₄H₂₂N₂O₃

[ Molecular Weight ]:
266.33600

[ Flash Point ]:
261.1ºC

[ Exact Mass ]:
266.16300

[ PSA ]:
84.58000

[ LogP ]:
1.54330

[ Index of Refraction ]:
1.54

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2924299090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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