2-(Fluorosulfonyl)difluoroacetic acid

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
197.8±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂HF₃O₄S

[ Molecular Weight ]:
178.087

[ Flash Point ]:
73.4±27.3 °C

[ Exact Mass ]:
177.954758

[ PSA ]:
79.82000

[ LogP ]:
2.18

[ Vapour Pressure ]:
0.2±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.389

Click to get detail MSDS

[ Symbol ]:

GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300-H310-H314

[ Precautionary Statements ]:
P264-P280-P302 + P350-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S27-S36/37/39

[ RIDADR ]:
UN 1760 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2915900090

Precursor

DownStream

[ HS Code ]: 2915900090

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

Facile one-pot synthesis of N-difluoromethyl-2-pyridone derivatives.

Org. Lett. 8(17) , 3805-8, (2006)

[reaction: see text] A novel one-pot synthesis of N-difluoromethyl-2-pyridones is described. N-(Pyridin-2-yl)acetamide derivatives were excellent precursors for the preparation of N-difluoromethyl-2-p...

Synthesis and biological evaluation of N-difluoromethyl-1,2-dihydropyrid-2-one acetic acid regioisomers: dual inhibitors of cyclooxygenases and 5-lipoxygenase.

Bioorg. Med. Chem. Lett. 20 , 2168-73, (2010)

A new group of acetic acid (7a-c, R(1) = H), and propionic acid (7d-f, R(1) = Me), regioisomers wherein a N-difluoromethyl-1,2-dihydropyrid-2-one moiety is attached via its C-3, C-4, and C-5 position ...

Preparation and use of a new difluorocarbene reagent Dolbier, W. R., Jr.; et al.

Organic Synth. 80 , 172-176, (2003)

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