4-(Difluoromethoxy)nitrobenzene

Names

[ Name ]:
4-(Difluoromethoxy)nitrobenzene

[Synonym ]:
MFCD00085009
Benzene, 1-(difluoromethoxy)-4-nitro-
Difluoromethyl 4-nitrophenyl ether
1-DIFLUOROMETHOXY-4-NITRO-BENZENE
4-Nitro-α,α-difluoroanisole
1-(Difluoromethoxy)-4-nitrobenzene
4-(Difluoromethoxy)nitrobenzene

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
259.6±30.0 °C at 760 mmHg

[ Melting Point ]:
37-40 °C(lit.)

[ Molecular Formula ]:
C₇H₅F₂NO₃

[ Molecular Weight ]:
189.116

[ Flash Point ]:
110.8±24.6 °C

[ Exact Mass ]:
189.023743

[ PSA ]:
55.05000

[ LogP ]:
2.21

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.494

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37

[ RIDADR ]:
3276

[ WGK Germany ]:
3

[ HS Code ]:
2909309090

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2909309090

[ Summary ]:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Use of fluoroform as a source of difluorocarbene in the synthesis of N-CF2H heterocycles and difluoromethoxypyridines. Thomoson CR, et al.

J. Fluor. Chem. 168 , 34-39, (2014)