αA-Conotoxin PIVA

Names

[ CAS No. ]:
171439-59-1

[ Name ]:
αA-Conotoxin PIVA

Biological Activity

[Description]:

αA-Conotoxin PIVA is a selective mouse musclenAChR inhibitor with IC50 for adult and fetal mouse musclenAChR sub> values are 2.3 nM and 22 nM respectively. αA-Conotoxin PIVA can be used in the study of neurological diseases.

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR
Signaling Pathways >> Neuronal Signaling >> nAChR
Research Areas >> Neurological Disease

[Target]

IC50: 2.3-22 nM (nAChR)[1].


[References]

[1]. Teichert RW, et al. Definition and characterization of the short alphaA-conotoxins: a single residue determines dissociation kinetics from the fetal muscle nicotinic acetylcholine receptor. Biochemistry. 2006 Jan 31;45(4):1304-12.  

Chemical & Physical Properties

[ Molecular Formula ]:
C103H150N34O37S6

[ Molecular Weight ]:
2648.89

Related Compounds

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