GNE-6468

Names

[ CAS No. ]:
1677668-27-7

[ Name ]:
GNE-6468

Biological Activity

[Description]:

GNE-6468 is a potent and selective RORγ(RORc) agonists with an EC50 value of 13 nM for HEK-293 cell.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> ROR

Research Areas >> Inflammation/Immunology

[References]

[1]. Fauber BP, et al. Discovery of imidazo[1,5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonists. Bioorg Med Chem Lett. 2015 Aug 1;25(15):2907-12.

[Related Small Molecules]

SR1078 | LYC-55716 | SR3335 | ROR gamma-t-IN-1 | SR1001 | GSK2981278 | SR2211 | Gne-0946 | L 601920-0 | RORγ-IN-1 | SR 0987 | TMP778

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₁₆ClN₃O₄

[ Molecular Weight ]:
433.84

Related Compounds

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