hMAO-B-IN-4
Names
[ CAS No. ]:
1666119-75-0
[ Name ]:
hMAO-B-IN-4
Biological Activity
[Description]:
hMAO-B-IN-4 (compound B10) is a selective, reversible and blood–brain barrier (BBB) penetrable human monoamine oxidase-B (hMAO-B) inhibitor with an IC50 value and a Ki value of 0.067 and 0.03 μM, respectively. hMAO-B-IN-4 inhibits hMAO-A with an IC50 value of 33.82 μM. hMAO-B-IN-4 can be used for Alzheimer’s disease (AD) and Parkinson’s disease (PD) research[1].
[Related Catalog]:
[In Vitro]
hMAO-B-IN-4 (0-40 μM) 对 hMAO-B 相比于 hMAO-A 具有高选择性,SI 值为 504.791[1]。 hMAO-B-IN-4 (0-40 μM) 抑制 hMAO-A 和 hMAO-B,IC50 值分别为 33.821 和 0.067 μM[1]。
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C20H16O2S
[ Molecular Weight ]:
320.40