4-(Chloromethyl)benzoic acid

Names

[ Name ]:
4-(Chloromethyl)benzoic acid

[Synonym ]:
alpa-Chloro-p-toluic acid
4-(Chloromethyl)benzoic acid
α-Chloro-p-toluic acid
4-CARBOXYBENZYL CHLORIDE
Alpha-Chloro-p-Toluic Acid
RARECHEM AL BO 0358
4-Chloro-p-toluic acid
EINECS 216-697-1
α-Chloro-p-toluylic acid
p-Carboxbenzyl chloride
p-carboxybenzyl chloride
MFCD00002568
Benzoic acid, 4-(chloromethyl)-
4-chlorotoluic acid
4-(Chloromethyl)benzoicacid

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
317.7±25.0 °C at 760 mmHg

[ Melting Point ]:
201-202 °C(lit.)

[ Molecular Formula ]:
C₈H₇ClO₂

[ Molecular Weight ]:
170.593

[ Flash Point ]:
145.9±23.2 °C

[ Exact Mass ]:
170.013458

[ PSA ]:
37.30000

[ LogP ]:
2.16

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.577

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314-H334

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C

[ Risk Phrases ]:
R34:Causes burns. R42/43:May cause sensitization by inhalation and skin contact . R36:Irritating to the eyes.

[ Safety Phrases ]:
S26-S36/37/39-S45-S22

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2916399090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

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Anal. Chim. Acta 862 , 77-85, (2015)

In this work, the anodic current at an electrode grafted with a molecularly imprinted polymer (MIP) crosslinked via a combination of hydrophobic ethyleneglycol dimethacrylate (EDMA) and hydrophilic me...

Design, synthesis, and discovery of stilbene derivatives based on lithospermic acid B as potent protein tyrosine phosphatase 1B inhibitors.

Bioorg. Med. Chem. Lett. 17 , 4481-6, (2007)

Dihydroxy stilbene derivatives were designed based on lithospermic acid B and were prepared from 4-(chloromethyl)benzoic acid. The inhibitory activities of the novel compounds against protein tyrosine...

Synthesis of nitroaromatic compounds as potential anticancer agents.

Anticancer Agents Med. Chem. 15(2) , 206-16, (2015)

Twenty-seven nitrated and non-nitrated compounds have been synthesized and tested for their growth inhibitory activity on three human cancer cells lines. Fourteen compounds were able to inhibit more t...