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SPD-473 citrate

Names

[ CAS No. ]:
161190-26-7

[ Name ]:
SPD-473 citrate

[Synonym ]:
Ethanone, 1-[1-(3,4-dichlorophenyl)cyclobutyl]-2-[[3-(dimethylamino)propyl]thio]-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) (salt)
1-[1-(3,4-Dichlorophenyl)cyclobutyl]-2-{[3-(dimethylamino)propyl]sulfanyl}ethanone 2-hydroxy-1,2,3-propanetricarboxylate (1:1)

Biological Activity

[Description]:

SPD-473 citrate is a serotonin/dopamine/norepinephrine reuptake inhibitior.

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> Dopamine Transporter
Signaling Pathways >> Neuronal Signaling >> Serotonin Transporter
Research Areas >> Neurological Disease

[Target]

serotonin/dopamine/norepinephrine reuptake


[In Vitro]

SPD-473 inhibits the synaptic reuptake of dopamine, serotonin and noradrenaline, making it a triple reuptake inhibitor potentially for the treatment of Parkinson's Disease.

[Related Small Molecules]

Fluoxetine Hydrochloride | Paroxetine HCl | Vanoxerine dihydrochloride | Sertraline hydrochloride | Fluvoxamine maleat | Fipexide | Duloxetine hydrochloride | Imipramine hydrochloride | Clomipramine HCl | Venlafaxine hydrochloride | Desvenlafaxine succinate | Doxepin hydrochloride | Vortioxetine | Milnacipran ((1S-cis) hydrochloride) | Vilazodone Hydrochloride

Chemical & Physical Properties

[ Molecular Formula ]:
C23H31Cl2NO8S

[ Molecular Weight ]:
552.465

[ Exact Mass ]:
551.114746

Related Compounds

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