Indirubin-3'-monoxime
Names
[ CAS No. ]:
160807-49-8
[ Name ]:
Indirubin-3'-monoxime
[Synonym ]:
3-(Hydroxyamino)-1H,2'H-2,3'-biindol-2'-one
2H-Indol-2-one, 3-[(3E)-1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-, (3Z)-
(3Z)-3-[(3E)-3-(Hydroxyimino)-1,3-dihydro-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one
Indirubin-3'-oxime
2H-Indol-2-one, 3-[3-(hydroxyamino)-1H-indol-2-yl]-
MFCD02683594
Indirubin-3'-monoxime
Biological Activity
[Description]:
[Related Catalog]:
[Target]
GSK-3β:22 nM (IC50)
CDK5/p25:100 nM (IC50)
CDK1/cyclin B:180 nM (IC50)
5-Lipoxygenase:7.8-10 μM (IC50)
[In Vitro]
[In Vivo]
[Kinase Assay]
[Cell Assay]
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
532.2±50.0 °C at 760 mmHg
[ Melting Point ]:
241 °C
[ Molecular Formula ]:
C16H11N3O2
[ Molecular Weight ]:
277.277
[ Flash Point ]:
275.7±30.1 °C
[ Exact Mass ]:
277.085114
[ PSA ]:
73.72000
[ LogP ]:
1.08
[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C
[ Index of Refraction ]:
1.772
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
[ HS Code ]:
2933990090
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%