H-D-Arg-OH

Names

[ CAS No. ]:
157-06-2

[ Name ]:
H-D-Arg-OH

[Synonym ]:
(R)-2-Amino-5-guanidinopentanoic acid
EINECS 205-866-5
H-D-Arg-OH
D-ARGININE BASE
R-(-)-ARGININE
D-ornithine, N-(diaminomethylene)-
(2R)-2-amino-5-guanidinopentanoic acid
D-Arg-OH
D-ARG.FREE BASE
D-2-Amino-5-guanidinovalerate
ARGININE,D
D-Arginine
N-(diaminomethylidene)-D-ornithine
D-(-)-ARGININE
MFCD00063116
D-Arg
D(-)-Arginine

Biological Activity

[Description]:

D-arginine (H-D-Arg-OH) is the D-isomer of arginine. Arginine is an α-amino acid that is used in the biosynthesis of proteins. D-Arginine is an inactive form of L-arginine[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Eduardo Navarro , et al. Toxicological and Pharmacological Effects of D-arginine. Basic Clin Pharmacol Toxicol. 2005 Sep;97(3):149-54.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
367.6±52.0 °C at 760 mmHg

[ Melting Point ]:
221-224ºC

[ Molecular Formula ]:
C₆H₁₄N₄O₂

[ Molecular Weight ]:
174.201

[ Flash Point ]:
176.1±30.7 °C

[ Exact Mass ]:
174.111679

[ PSA ]:
125.22000

[ LogP ]:
-1.79

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.601

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
CF1934220

[ HS Code ]:
2925290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2925290090

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Cloning a neutral protease of Clostridium histolyticum, determining its substrate specificity, and designing a specific substrate.

Appl. Microbiol. Biotechnol. 99 , 10489-99, (2015)

Islet transplantation is a prospective treatment for restoring normoglycemia in patients with type 1 diabetes. Islet isolation from pancreases by decomposition with proteolytic enzymes is necessary fo...

Arginase promotes skeletal muscle arteriolar endothelial dysfunction in diabetic rats.

Front. Immunol. 4 , 119, (2013)

Endothelial dysfunction is a characteristic feature in diabetes that contributes to the development of vascular disease. Recently, arginase has been implicated in triggering endothelial dysfunction in...

Simultaneous determination of 18 D-amino acids in rat plasma by an ultrahigh-performance liquid chromatography-tandem mass spectrometry method: application to explore the potential relationship between Alzheimer's disease and D-amino acid level alterations.

Anal. Bioanal. Chem 408 , 141-50, (2016)

D-Amino acids are increasingly being recognized as important signaling molecules, and abnormal levels of D-amino acids have been implicated in the pathogenesis of Alzheimer's disease. To evaluate the ...

Related Compounds

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