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Ac-Lys-AMC

Names

[ CAS No. ]:
156661-42-6

[ Name ]:
Ac-Lys-AMC

[Synonym ]:
Ac-Lys-AMC (Acetate salt)
N2-acetyl-L-lysine 4-methylcoumar-7-ylamide
H-(N-acetyl-Lys)-AMC

Biological Activity

[Description]:

Ac-Lys-AMC (Hexanamide), also termed MAL, is a fluorescent substrate for histone deacetylase HDACs[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC
Signaling Pathways >> Epigenetics >> HDAC

[References]

[1]. Heltweg B, et al. Nonisotopic substrate for assaying both human zinc and NAD+-dependent histone deacetylases. Anal Biochem. 2003 Aug 1;319(1):42-8.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H23N3O4

[ Molecular Weight ]:
345.39300

[ Exact Mass ]:
345.16900

[ PSA ]:
121.41000

[ LogP ]:
3.86370


Related Compounds