Ac-Arg-Gly-Lys-AMC trifluoroacetate salt

Names

[ Name ]:
Ac-Arg-Gly-Lys-AMC trifluoroacetate salt

[Synonym ]:
L-Lysinamide, N2-acetyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
N2-Acetyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide
Ac-Arg-Gly-Lys-AMC trifluoroacetate salt

Biological Activity

[Description]:

Ac-Arg-Gly-Lys-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Arg-Gly-Lys-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Noonepalle S, et, al. Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models. J Med Chem. 2020 Sep 24;63(18):10246-10262.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₂₆H₃₈N₈O₆

[ Molecular Weight ]:
558.63

[ Exact Mass ]:
558.291443

[ LogP ]:
-1.07

[ Index of Refraction ]:
1.640

Related Compounds

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