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Pamiparib

Names

[ CAS No. ]:
1446261-44-4

[ Name ]:
Pamiparib

[Synonym ]:
(10aR)-2-Fluoro-10a-methyl-5,8,9,10,10a,11-hexahydro-5,6,7a,11-tetraazacyclohepta[1,2,3,4-def]cyclopenta[a]fluoren-4(7H)-one
pamiparib
5,6,7a,11-Tetraazacyclohepta[def]cyclopenta[a]fluoren-4(7H)-one, 2-fluoro-5,8,9,10,10a,11-hexahydro-10a-methyl-, (10aR)-
8375F9S90C

Biological Activity

[Description]:

Pamiparib is a PARP inhibitor which can be used for the treatment of various cancers including the solid tumor, extracted from patent WO 2013097225 A1.

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> PARP
Signaling Pathways >> Epigenetics >> PARP
Research Areas >> Cancer

[Target]

PARP


[References]

[1]. Changyou Zhou, et al. Fused tetra or penta-cyclic dihydrodiazepinocarbazolones as parp inhibitors. WO 2013097225 A1.


[Related Small Molecules]

Talazoparib | XAV-939 | MK-4827(Niraparib) | Veliparib (ABT-888) | Rucaparib (AG-014699) phosphate | PJ34 HCl | Rucaparib camsylate | E-7449 | AZD2461 | G007-LK | Iniparib (BSI-201) | NMS-P118 | A-966492 | AG14361 | JW55

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Molecular Formula ]:
C16H15FN4O

[ Molecular Weight ]:
298.315

[ Exact Mass ]:
298.122986

[ LogP ]:
0.02

[ Index of Refraction ]:
1.829

[ Storage condition ]:
-20℃

Related Compounds