Mesterolone

Names

[ Name ]:
Mesterolone

[Synonym ]:
17β-Hydroxy-1α-methyl-5α-androstan-3-one
EINECS 215-836-3
4,5a-Dihydro-1a-methyltestosterone
1a-Methyl-5a-dihydrotestosterone
(1a,5a,17b)-17-Hydroxy-1-methylandrostan-3-one
Proviron
1a-Methyl-5a-androstan-17b-ol-3-one
17b-Hydroxy-1a-methyl-5a-androstan-3-one
5α-Androstan-3-one, 17β-hydroxy-1α-methyl-
Mesterolone
(1S,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-1,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
1α-Methyl-5α-dihydrotestosterone
MFCD00133082
(1α,5α,17β)-17-Hydroxy-1-methylandrostan-3-one
Androstan-3-one, 17-hydroxy-1-methyl-, (1α,5α,17β)-

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
420.3±45.0 °C at 760 mmHg

[ Melting Point ]:
208 °C

[ Molecular Formula ]:
C₂₀H₃₂O₂

[ Molecular Weight ]:
304.467

[ Flash Point ]:
179.4±21.3 °C

[ Exact Mass ]:
304.240234

[ PSA ]:
37.30000

[ LogP ]:
4.24

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.525

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BV8063400

CHEMICAL NAME :: 5-alpha-Androstan-3-one, 17-beta-hydroxy-1-alpha-methyl-

CAS REGISTRY NUMBER :: 1424-00-6

LAST UPDATED :: 198910

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H32-O2

MOLECULAR WEIGHT :: 304.52

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 600 ug/kg

SEX/DURATION :: female 4 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - other measures of fertility

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 16,455,1966

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H332

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S22-S24/25-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
BV8063400

[ HS Code ]:
2942000000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2942000000

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A benchmark data set of steroids with known affinity for sex hormone-binding globulin (SHBG) has been widely used to validate popular molecular field-based QSAR techniques. We have expanded the data s...

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J. Anal. Toxicol. 38(9) , 637-44, (2014)

A screening method for 18 frequently measured exogenous anabolic steroids and the testosterone/epitestosterone (T/E) ratio in forensic cases has been developed and validated. The method involves a ful...

Osteoporosis in male hypogonadism: responses to androgen substitution differ among men with primary and secondary hypogonadism.

Horm. Res. 60(1) , 21-8, (2003)

No randomized study exists comparing the effects of different modes of androgen substitution on bone mineral density (BMD).We performed a prospective, randomized, trial assigning 53 hypogonadal men to...

Related Compounds

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