Diosgenin glucoside

Names

[ Name ]:
Diosgenin glucoside

[Synonym ]:
Diosgenin 3-b-D-glucoside
β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl
Diosgenin 3-O-b-D-glucopyranoside
PolyphyllinA
Diosgenin b-D-glucoside
Polyphyllin A
Funkioside A
Diosgenin 3-glucoside
Collettinside I
Melongoside B
Diosgenin glucoside
(25R)-3β-(β-D-Glucopyranosyloxy)spirost-5-ene
(25R)-3b-(b-D-Glucopyranosyloxy)spirost-5-ene
Disogluside
Prosapogenin D'3
Lilioglycoside A
Alliumoside A
Polygonatoside A
Trillin
(3β,25R)-Spirost-5-en-3-yl β-D-glucopyranoside
Collettiside I

Biological Activity

[Description]:

Diosgenin glucoside, a saponin compound extracted from Tritulus terrestris L., provides neuroprotection by regulating microglial M1 polarization. Diosgenin glucoside protects against spinal cord injury by regulating autophagy and alleviating apoptosis [1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Signaling Pathways >> Autophagy >> Autophagy

Research Areas >> Inflammation/Immunology

Research Areas >> Neurological Disease

[References]

[1]. Int Immunopharmacol. 2017 Sep;50:22-29. doi: 10.1016/j.intimp.2017.06.008. Epub 2017 Jun 14.

[2]. Chen XB, et al. Diosgenin Glucoside Protects against Spinal Cord Injury by Regulating Autophagy and Alleviating Apoptosis. Int J Mol Sci. 2018 Aug 2;19(8). pii: E2274.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
705.1±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₃H₅₂O₈

[ Molecular Weight ]:
576.761

[ Flash Point ]:
380.2±32.9 °C

[ Exact Mass ]:
576.366211

[ PSA ]:
117.84000

[ LogP ]:
3.89

[ Vapour Pressure ]:
0.0±5.1 mmHg at 25°C

[ Index of Refraction ]:
1.594

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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