14144-06-0

14144-06-0 structure

Name: Diosgenin glucoside
Chemical Name: Trillin
CAS Number: 14144-06-0
Molecular Formula: C₃₃H₅₂O₈
Molecular Weight: 576.761
Catalog: Biochemical Natural product
Create Date: 2018-08-29 19:01:36
Modify Date: 2025-08-22 08:33:55
Diosgenin glucoside, a saponin compound extracted from Tritulus terrestris L., provides neuroprotection by regulating microglial M1 polarization. Diosgenin glucoside protects against spinal cord injury by regulating autophagy and alleviating apoptosis [1][2].

Name	Trillin
Synonyms	Diosgenin 3-b-D-glucoside β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl Diosgenin 3-O-b-D-glucopyranoside PolyphyllinA Diosgenin b-D-glucoside Polyphyllin A Funkioside A Diosgenin 3-glucoside Collettinside I Melongoside B Diosgenin glucoside (25R)-3β-(β-D-Glucopyranosyloxy)spirost-5-ene (25R)-3b-(b-D-Glucopyranosyloxy)spirost-5-ene Disogluside Prosapogenin D'3 Lilioglycoside A Alliumoside A Polygonatoside A Trillin (3β,25R)-Spirost-5-en-3-yl β-D-glucopyranoside Collettiside I

Description	Diosgenin glucoside, a saponin compound extracted from Tritulus terrestris L., provides neuroprotection by regulating microglial M1 polarization. Diosgenin glucoside protects against spinal cord injury by regulating autophagy and alleviating apoptosis [1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Autophagy >> Autophagy Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
References	[1]. Int Immunopharmacol. 2017 Sep;50:22-29. doi: 10.1016/j.intimp.2017.06.008. Epub 2017 Jun 14. [2]. Chen XB, et al. Diosgenin Glucoside Protects against Spinal Cord Injury by Regulating Autophagy and Alleviating Apoptosis. Int J Mol Sci. 2018 Aug 2;19(8). pii: E2274.