Prosapogenin A

Names

[ CAS No. ]:
19057-67-1

[ Name ]:
Prosapogenin A

[Synonym ]:
Prosapogenin A
(3β,25R)-Spirost-5-en-3-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-
polyphyllin V
Progenin III

Biological Activity

[Description]:

Prosapogenin A, a natural product from Veratrum, induces apoptosis in human cancer cells in vitro via inhibition of the STAT3 signaling pathway and glycolysis[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

[References]

[1]. Wang TX, et al. Prosapogenin A induces apoptosis in human cancer cells in vitro via inhibition of the STAT3 signaling pathway and glycolysis. Oncol Lett. 2013 Nov;6(5):1323-1328.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
838.8±65.0 °C at 760 mmHg

[ Melting Point ]:
212℃

[ Molecular Formula ]:
C₃₉H₆₂O₁₂

[ Molecular Weight ]:
722.902

[ Flash Point ]:
461.1±34.3 °C

[ Exact Mass ]:
722.424133

[ PSA ]:
176.76000

[ LogP ]:
6.90

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.605

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Related Compounds

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