Azido-PEG2-alcohol

Names

[ Name ]:
Azido-PEG2-alcohol

[Synonym ]:
2-(2-azidoethoxy)ethan-1-ol
2-(2-azidoethoxy)-ethanol
5-azido-3-oxapentanol
5-azido-3-oxa-1-pentanol
Azido-PEG2
(2-azidoethoxy)ethanol
Ethanol,2-(2-azidoethoxy)

Biological Activity

[Description]:

Azido-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

[ Molecular Formula ]:
C₄H₉N₃O₂

[ Molecular Weight ]:
131.13300

[ Exact Mass ]:
131.06900

[ PSA ]:
79.21000

[ Storage condition ]:
-20°C

Azido-PEG2-alcohol

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds