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139115-90-5

139115-90-5 structure
139115-90-5 structure
  • Name: Azido-PEG2-alcohol
  • Chemical Name: 2-(2-azidoethoxy)ethanol
  • CAS Number: 139115-90-5
  • Molecular Formula: C4H9N3O2
  • Molecular Weight: 131.13300
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2016-02-12 10:18:39
  • Modify Date: 2024-01-09 11:15:29
  • Azido-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-(2-azidoethoxy)ethanol
Synonyms 2-(2-azidoethoxy)ethan-1-ol
2-(2-azidoethoxy)-ethanol
5-azido-3-oxapentanol
5-azido-3-oxa-1-pentanol
Azido-PEG2
(2-azidoethoxy)ethanol
Ethanol,2-(2-azidoethoxy)
Description Azido-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C4H9N3O2
Molecular Weight 131.13300
Exact Mass 131.06900
PSA 79.21000
Storage condition -20°C
Precursor  2

DownStream  1